Introduction Non-alcoholic steatohepatitis (NASH) is the most recurrent form of chronic liver disease. There are two patterns of NASH; cholestatic (affecting bile ducts, reducing bile flow) and hepatitic, with the cholestatic pattern associated with more...
The liver connects the intestinal portal vasculature with the general circulation. It consists of hexagonal units called lobules that not only ensure efficient metabolism but also organize immune cells in a strategic topographical distribution. The...
Messenger RNA (mRNA)‑based therapeutics confer less risk due to the transient nature of expression and with the success of the COVID‑19 vaccinations, a greater confidence in their safety has resulted in more therapies progressing to...
Kidney fibrosis is the hallmark of chronic kidney disease (CKD) progression; however, no current antifibrotic therapies exist due to the intricate cellular mechanisms involved in fibrosis and the origin of scar-forming cells in human kidney...
Introduction Pulmonary fibrosis is a serious lung disease characterised by the spontaneous buildup of scar tissue in the absence of infectious or autoimmune diseases. It has a poor prognosis, with a 50% three-year survival rate,...
