Spotlights

Oncology

Epigenetic memory of colitis promotes tumour growth

Introduction Inflammation is a major risk factor for cancer, but the underlying molecular mechanisms remain unclear. There are well-established clinical associations between inflammation in the gut and cancer and patients with ulcerative colitis (UC) are...

Oncology

A cfDNA methylation-based tissue-of-origin classifier for cancers of...

Introduction Cancer of unknown primary (CUP) is a rare disease in which malignant cells are present while the originating organ remains unknown. This makes it difficult to treat, as selecting an appropriate therapy is problematic...