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Bioinformatics

In-House Bioinformatician Providing Data Analysis and Biological Interpretation

Epistem recognises the significance of analysing next-generation sequencing (NGS) data and therefore provides personalised bioinformatic analysis services to meet your research requirements.
Bioinformatic analysis may include demultiplexing of samples and raw data QC, genome alignment, identification of differentially expressed genes, pathway analysis and biomarker signature identification and assessment. Where relevant public datasets are available, signature biomarkers can be assessed in independent studies.

An Overview

Unbiased and Focused Analysis

Epistem offers a comprehensive data analysis service that includes unbiased analysis of differentially expressed genes between relevant comparison groups, with subsequent biological interpretation. Our team also conducts focused analysis of the behaviour of genes or pathways of interest, if required.
Epistem undertakes comprehensive analysis of data using specialised software packages. This includes unbiased interrogation of genes differentially expressed between relevant comparison groups and focused analysis of genes or pathways of interest. Standard analysis includes comprehensive statistical analysis and ANOVAs based on group experimental factors.

Epistem conducts biological interpretation and pathway analysis using specialised software packages, enabling accurate interpretation of genomics data.
The Broad Institute Connectivity map is used to link gene patterns associated with disease to corresponding patterns produced by drug candidates. Epistem also specialises in deciphering gene expression information to obtain gene expression signatures relevant to specific compounds that can be used in clinical settings to monitor drug treatment.

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